Aims and Objectives
Antimicrobial resistance is one of the most urgent threats facing people from all parts of the world. During the last six years the ISAC Antimicrobial Stewardship Working Group has been increasing its membership composition, having now over 40 international members from the five continents.
Our group also has a large and very active Antimicrobial Stewardship African Network, in conjunction with the Infection Control African Network (ICAN).
Both the ISAC AMS and the African Network groups are integrated by a wide variety of health-care workers (physicians of different specialities, microbiologists, epidemiologists, pharmacists and nurses) committed to a real improvement in the global use of antimicrobials.
Our current aims are:
- To enhance a worldwide net of health-care workers involved and committed to a real improvement in the use of antimicrobials.
- To develop surveys investigating several related issues of antimicrobial use in different circumstances, antimicrobial consumption, composition and productions of antimicrobial stewardship programmes, etc.
- To continue the production of transcontinental consensus documents addressing prevalent issues related to the judicious use of antimicrobials, as the rational management of multi-drug resistant bacteria, and general recommendations for the prudent use of antimicrobials in different settings (i.e., community, inpatients, special patients, etc.)
- To continue running distance learning courses in different countries and continents, with a very low or no- cost for participants.
During 2014 the ISC AMS working group has been present in the following international scientific meetings:
|2 – 4 May 2014
5th ISC MRSA Consensus Conference “MRSA – Unfinished Business”.
Co-organized with the Antimicrobial Resistance Working Group
|21- 24 May 2014
Sao Paulo Congress of Infectious Diseases, Brazil.
Antimicrobial Stewardship session, co-organized with ISC
|14 - 16 October 2014
||8th Cuban Congress of Microbiology and Parasitology, La Habana, Cuba.
Antimicrobial Stewardship and Treatment of MDR Gram negative infections sessions
|3-8 November 2014
||5th ICAN Conference, Harare, Zimbabwe.
Conferences sessions: Prevention and treatment of MRSA and MDR Gram negative infections. After the ICAN conference, a day and a half workshop was done, with the presence of 150 participants from many African countries
|26- 29 November 2014
15th Asia Pacific Congress of Clinical Microbiology and Infection (APCCMI) , Kuala Lumpur, Malaysia.
Symposium: Antimicrobial Stewardship in different scenarios: Problems and solutions (Organized in collaboration with the ISC Antimicrobial Resistance Working Group).
|18 May 2015
Pan-american Congress of Infectious Diseases, Quito, Ecuador. Symposium - Antibiotic Stewardship and Resistance
|17-22 November 2015
Infection Prevention Control Network of Kenya/ICAN. Two participations on the conference, and co-organization and presentations at the Antimicrobial Stewardship Workshop
Projects / Publications
Infection Control African Network: the joint Infection Control African Network (ICAN)/ISC Antimicrobial Stewardship network now count 43 members from across Africa. Since 2012 we are co-organizing once a year a two-days workshop on Infection Control & Antimicrobial Stewardship. The first was held in Cape Town, South Africa (November 2012), the second in Mombasa, Kenya (November 2013), the third in Harare, Zimbabwe (November 2014) and the next will be held in Naivasha, Kenya in November 2015.
World Alliance Against Antibiotic Resistance (WAAAR): we have actively participated in the elaboration of many documents, including the recently launched international declaration http://www.ac2bmr.fr/index.php/en/
European Study Group of Antibiotic Policies (ESGAP): we have jointly organized an international cross-sectional survey of antimicrobial stewardship programmes in hospitals. This has been presented in several conferences and published in JAC on December 2014.
Treatment of serious infections due to carbapenem-resistant Enterobacteriaceae (CRE): Co-organized with the Antimicrobial Resistance Working Group. This is a global survey consisting in 8 clinical cases that aimed to analyze how physicians treat infections due to MDR Enterobacteriaceae. Around 2000 responses cumulated to all cases has been received, and results are being processed for publication.
Key points for the appropriate use of antibiotics in hospitalised patients: This new position paper is very advanced.
Distance learning course “BASICS IN ANTIMICROBIAL STEWARDSHIP AND INFECTION CONTROL” (BASIC) 2014 for Africa, co-organized with ICAN: The first version of this course was held between September 2014 and February 2015, and convened 150 participants including physicians, clinical pharmacists, clinical microbiologists and nurses from all African countries involved or interested in developing antimicrobial stewardship and IPC activities. The course contained 5 educational modules and interactive forums of discussions, and has been very successful and well received.
|Antimicrobial Stewardship Working Group
||“Ten Commandments” for the appropriate use of antibiotics by the practicing physician in an outpatient setting. Front Microbiol. 2011; 2:230
|Levy Hara G, Gould I, Endimiani A, Pardo PR, Daikos G, Hsueh PR
||Detection, treatment, and prevention of carbapenemase-producing Enterobacteriaceae: Recommendations from an International Working Group. J Chemother. 2013; 25(3):129-40.
|Tambyah PA, Levy Hara G, Daikos G, Falagas M, Mazzei T, Mouton J
||Treatment of extensively drug-resistant Gram-negative infections in critically ill patients: Outcome of a consensus meeting at the 13th Asia-Pacific Congress of Clinical Microbiology and Infection, October 2012. J Global Antimicrob Resist (2013),http://dx.doi.org/10.1016/j.jgar.2013.04.002
|Wertheim H, Van Nguyen K, Levy Hara G, Gelband H, Laxminarayan R, Mouton J, Cars O
||Global survey of polymyxin use: A call for international guidelines. J Global Antimicrob Resist (2013), http://dx.doi.org/10.1016/j.jgar.2013.03.012
|Laxminarayan R, Duse A, Wattal C, Zaidi AK, Wertheim HF, Sumpradit N, Vlieghe E, Levy Hara G, Gould IM
||Antibiotic resistance-the need for global solutions. Lancet Infect Dis. 2013 Dec;13(12):1057-98.
|Levy Hara G
||Antimicrobial stewardship in hospitals: Does it work and can we do it?. J Global Antimicrob Resist 2014; 2 (1):1–6
|P. Howard; C. Pulcini; G. Levy Hara; R. M. West; I. M. Gould; S. Harbarth; D. Nathwani
||An international cross-sectional survey of antimicrobial stewardship programmes in hospitals J Antimicrob Chemother. 2015; 70(4):1245-55.